Current Advances in Drug Delivery Systems
- Prof. Dr. Horacio CABRAL, The University of Tokyo, Department of Bioengineering
- Prof. Dr. Frederico PITTELLA, Universidade Federal de Juiz de Fora, Department of Pharmaceutical Sciences
Drug Delivery Systems have emerged as an effective tool for the treatment of various disease conditions. These systems refer to the technology used to modulate and optimize the delivery of medicines towards a therapeutic effect by decreasing or avoiding degradation, inefficient absorption, immunogenic and drug toxicity adverse effects. Thus, the approaches include efficient drug delivery strategies to reach the exact location in the body at optimal concentrations by passive and active targeting, the release based on physiological differences between healthy and diseased tissue and the recognition of targets from a specific site at the affected tissue. In addition to targeted delivery the drugs, its route of administration and drug formulations are also important challenges both for pharmacological and diagnostic purposes. Therefore, drug delivery systems for carrying medicines to specific sites of the body are dynamic and broad field, which allows advancements towards better treatment and prognosis. Still, there is plenty a room for development down to the nanoscale, based on theoretical rationale and experimental proof. In addition, a broad range of biomaterials are able to be applied to the construction of nanodevices for drug release, and it includes polymers, lipids, inorganic salts, among others. Finally, this session is of great relevance for the BMS community and aims to bring together researchers working on Drug Delivery Systems of distinct nature, to discuss the path from bench to clinical applications.